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Hematopoetic Malignancies

Through a licensing agreement with the Barbara Ann Karmanos Cancer Institute (formerly part of Wayne State University), Asterand provides well characterized human cell lines derived from patients with hematopoetic malignancies.  These cell lines, developed by Drs. Ayad Al-Katib and Ramzi Mohammad, will be of interest to researchers seeking a cure for lymphoma, leukemia, pancreatic cancer, and macroglobulinema.
All cell lines are provided in cryovial of ~1x106 cells.
 
All of the cell lines available from Asterand were developed in conjunction with different academic institutions.  As a result of our agreements with these institutions, we offer our cell lines to academic and governmental researchers at prices lower than those available to our commercial customers.  If you have any questions about this policy, please please email us at ecommerce@asterand.com.
 
 
 
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WSU-AML

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WSU-AML, a new human aggressive AML cell line, was established from frozen peripheral blood of a patient with AML. The cell line showed a partial interstitial deletion of the long arm (q) of chromosome 9.  Phenotypically, the cell line is consistent with a diagnosis of M7 AML.

WSU-DLCL2

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WSU-DLCL2, a human diffuse large cell lymphoma cell line, is a mature B-cell line (IgG l) that is negative for EBV nuclear antigen, expresses the multi-drug resistance phenotype, and has t (14;18) (q32;q21) plus other chromosomal aberrations.
WSU-FSCCL

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WSU-FSCCL, a human B-cell line, was established from an EBV-negative low-grade follicular small cleaved cell Lymphoma in leukemic phase.

WSU-NHL

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WSU-NHL was established from a malignant pleural effusion occurring in a patient with nodular histiocytic (follicular, large cell) lymphoma.

WSU-Pre-B-ALL

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WSU-Pre-B-ALL, a new human EBV negative pre-B-Acute Lymphoblastic Leukemia, was established from frozen peripheral blood of a patient with ALL in leukemic phase.  Both the frozen cells and the established cell line exhibit t (1;19) chromosomal translocation, partial deletion of the short arm (p) of chromosome 9 and a loss of chromosome 13 as clonal abnormalities.
WSU-WM

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WSU-WM was established from pleural effusion from a patient with IgMk Waldenstrom?s macroglobulinemia (WM) which is a human B-cell tumor.