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B3GALNT1 v1, 2, 3, 4, 5 XpressWay Gene Expression Profile

 
US Price: $2,000.00

Stock Status:In Stock

Description
 
B3GALNT1-v1_2_3_4_5

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein. [provided by RefSeq, Jul 2008]
B3GALNT1-v1_2_3_4_5

Swiss Description: UDP-GalNAc:beta-1 3-N-acetylgalactosaminyltransferase 1; Beta-3-GalNAc-T1; Beta-1 3-galactosyltransferase 3; Beta-3-Gx-T3; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1 3-N-acetylgalactosaminyltransferase; Globoside synthase

N_Accession: NM_003781
P_accession: O75752

With Asterand’s TargetEvaluator® database consisting of more than 2000 XpressWay® Gene Expression Profiles, you are sure to find a target of interest. XpressWay® Profiles consist of high quality target expression in 72 normal human tissues from 3 different donors. The tissues are chosen to be representative of the major organ systems of the human body, and comprise many sub-dissected regions. Total RNA is isolated from tissues using Asterand’s standard methodologies, and gene expression is measured using highly sensitive and quantitative real time-PCR. Target gene transcripts are multiplexed with GAPDH as a control for the PCR process. Each XpressWay Sample Report presents visual expression profiles and a complete data set for your gene of interest. Click here for full details of Asterand's qRT-PCR methodologies used to generate XpressWay Profiles.

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