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ADRA2C XpressWay Gene Expression Profile

 
Our Price: $2,000.00

Stock Status:In Stock

Description
 
ADRA2C Xpressway Gene Expression Profile

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
ADRA2C

Swiss Description: Alpha-2C adrenergic receptor; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2 adrenergic receptor subtype C4

N_Accession: NM_000683
P_accession: P18825

With Asterand’s TargetEvaluator® database consisting of more than 2000 XpressWay® Gene Expression Profiles, you are sure to find a target of interest. XpressWay® Profiles consist of high quality target expression in 72 normal human tissues from 3 different donors. The tissues are chosen to be representative of the major organ systems of the human body, and comprise many sub-dissected regions. Total RNA is isolated from tissues using Asterand’s standard methodologies, and gene expression is measured using highly sensitive and quantitative real time-PCR. Target gene transcripts are multiplexed with GAPDH as a control for the PCR process. Each XpressWay Sample Report presents visual expression profiles and a complete data set for your gene of interest. Click here for full details of Asterand's qRT-PCR methodologies used to generate XpressWay Profiles.

Profiles are purchased with a license and you will be provided in a full profile report. While any number of profiles may be purchased, if you are purchasing more than 20 profiles, please contact advantage@asterand.com so that your Regional Business Development Director may contact you for special tiered pricing.