Home > Human Gene Profiles >

ACVR2 XpressWay Gene Expression Profile

 
US Price: $2,000.00

Stock Status:In Stock

Description
 
ACVR2 Xpressway Gene Expression Profile

Several ligands that signal through the Activin type II receptors regulate muscle growth. Myostatin, a TGF-beta superfamily member, is a negative regulator of muscle growth. Myostatin binds to ACVR2B and to a lesser extent ACVR2A. In mice that were ACVR2A ?/? mutants there was an increase in all four muscle groups studied (pectoralis, triceps, quadriceps, and gastrocnemious/plantaris muscles). Two of these muscle groups (pectoralis and triceps) were increased in ACVR2B ?/? mutants.
ACVR2

Swiss Description: Activin receptor type-2A; Activin receptor type IIA

N_Accession: NM_001616
P_accession: P27037

With Asterand’s TargetEvaluator® database consisting of more than 2000 XpressWay® Gene Expression Profiles, you are sure to find a target of interest. XpressWay® Profiles consist of high quality target expression in 72 normal human tissues from 3 different donors. The tissues are chosen to be representative of the major organ systems of the human body, and comprise many sub-dissected regions. Total RNA is isolated from tissues using Asterand’s standard methodologies, and gene expression is measured using highly sensitive and quantitative real time-PCR. Target gene transcripts are multiplexed with GAPDH as a control for the PCR process. Each XpressWay Sample Report presents visual expression profiles and a complete data set for your gene of interest. Click here for full details of Asterand's qRT-PCR methodologies used to generate XpressWay Profiles.

Profiles are purchased with a license and you will be provided in a full profile report. While any number of profiles may be purchased, if you are purchasing more than 20 profiles, please contact advantage@asterand.com so that your Regional Business Development Director may contact you for special tiered pricing.