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AADAT Xpressway Gene Expression Profile

 
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Description
 
AADAT Xpressway Gene Expression Profile

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

Swiss Description: Kynurenine/alpha-aminoadipate aminotransferase mitochondrial precursor (KAT/AadAT) (Kynurenine--oxoglutarate transaminase II) (EC 2.6.1.7) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (EC 2.6.1.39)

This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene.

N_Accession: NM_182662
Protein Symbol:
Q8N5Z0-AADAT_HUMAN
Recommended name:
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Protein Accession:
Q8N5Z0
Secondary Accessions:
  • B3KP84
  • Q9UL02


With Asterand’s TargetEvaluator® database consisting of more than 2000 XpressWay® Gene Expression Profiles, you are sure to find a target of interest. XpressWay® Profiles consist of high quality target expression in 72 normal human tissues from 3 different donors. The tissues are chosen to be representative of the major organ systems of the human body, and comprise many sub-dissected regions. Total RNA is isolated from tissues using Asterand’s standard methodologies, and gene expression is measured using highly sensitive and quantitative real time-PCR. Target gene transcripts are multiplexed with GAPDH as a control for the PCR process. Each XpressWay Sample Report presents visual expression profiles and a complete data set for your gene of interest. Click here for full details of Asterand's qRT-PCR methodologies used to generate XpressWay Profiles.

Profiles are purchased with a license and you will be provided in a full profile report. While any number of profiles may be purchased, if you are purchasing more than 20 profiles, please contact advantage@asterand.com so that your Regional Business Development Director may contact you for special tiered pricing.